National Highways: Yorkshire said two lanes were closed between the M18 junction for Hatfield and junction one for Tudworth.
The agency said a car and a lorry were involved in a crash, which left the car on its roof. Delays are building on the M180 and the M18 itself.
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The crash is thought to have happened at around 7.30am. There are no reports of injuries currently.
Delays are building on the M18
It tweeted: “2 (of 3) lanes closed on the #M180 eastbound between #M18 #Hatfield and J1 (#Tudworth), due to a collision involving a car and lorry. The car has overturned and come to rest on its roof. Delays are building on the #M18.”
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